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Dynamic binding of RBPJ is determined by Notch signaling status

Notch signaling plays crucial roles in mediating cell fate choices in all metazoans largely by specifying the transcriptional output of one cell in response to a neighboring cell. The DNA-binding protein RBPJ is the principle effector of this pathway in mammals and, together with the transcription f...

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Autores principales: Castel, David, Mourikis, Philippos, Bartels, Stefanie J.J., Brinkman, Arie B., Tajbakhsh, Shahragim, Stunnenberg, Hendrik G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656323/
https://ncbi.nlm.nih.gov/pubmed/23651858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.211912.112
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