A SILAC-Based Screen for Methyl-CpG Binding Proteins Identifies RBP-J as a DNA Methylation and Sequence-Specific Binding Protein

BACKGROUND: DNA methylation is an epigenetic modification that plays a crucial role in a variety of biological processes. Methylated DNA is specifically bound by Methyl-CpG Binding Proteins (MBPs). Three different types of MBPs have been identified so far: the Methyl-CpG Binding Domain (MBD) family...

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Main Authors: Bartels, Stefanie J. J., Spruijt, Cornelia G., Brinkman, Arie B., Jansen, Pascal W. T. C., Vermeulen, Michiel, Stunnenberg, Hendrik G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185043/
https://ncbi.nlm.nih.gov/pubmed/21991380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025884
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