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Plekhg4 Is a Novel Dbl Family Guanine Nucleotide Exchange Factor Protein for Rho Family GTPases

Mutations in the PLEKHG4 (puratrophin-1) gene are associated with the heritable neurological disorder autosomal dominant spinocerebellar ataxia. However, the biochemical functions of this gene product have not been described. We report here that expression of Plekhg4 in the murine brain is developme...

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Hlavní autoři: Gupta, Meghana, Kamynina, Elena, Morley, Samantha, Chung, Stacey, Muakkassa, Nora, Wang, Hong, Brathwaite, Shayna, Sharma, Gaurav, Manor, Danny
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656306/
https://ncbi.nlm.nih.gov/pubmed/23572525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.430371
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