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Regulation of Proto-Oncogenic Dbl by Chaperone-Controlled, Ubiquitin-Mediated Degradation

The dbl proto-oncogene product is a prototype of a growing family of guanine nucleotide exchange factors (GEFs) that stimulate the activation of small GTP-binding proteins from the Rho family. Mutations that result in the loss of proto-Dbl's amino terminus produce a variant with constitutive GE...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kamynina, Elena, Kauppinen, Krista, Duan, Faping, Muakkassa, Nora, Manor, Danny
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820456/
https://ncbi.nlm.nih.gov/pubmed/17178836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01051-06
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