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Hyperoxidation of Peroxiredoxins 2 and 3: RATE CONSTANTS FOR THE REACTIONS OF THE SULFENIC ACID OF THE PEROXIDATIC CYSTEINE
Typical 2-Cys peroxiredoxins (Prxs) react rapidly with H(2)O(2) to form a sulfenic acid, which then condenses with the resolving cysteine of the adjacent Prx in the homodimer or reacts with another H(2)O(2) to become hyperoxidized. Hyperoxidation inactivates the Prx and is implicated in cell signali...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3656273/ https://ncbi.nlm.nih.gov/pubmed/23543738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.460881 |
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