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Amplified DNAs in laboratory stocks of Leishmania tarentolae: extrachromosomal circles structurally and functionally similar to the inverted-H-region amplification of methotrexate-resistant Leishmania major.

We describe the structure of amplified DNA that was discovered in two laboratory stocks of the protozoan parasite Leishmania tarentolae. Restriction mapping and molecular cloning revealed that a region of 42 kilobases was amplified 8- to 30-fold in these lines. Southern blot analyses of digested DNA...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Mol Cell Biol
Ngā kaituhi matua: Petrillo-Peixoto, M L, Beverley, S M
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Taylor & Francis 1988
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365621/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3244352/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.12.5188-5199.1988
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