Amplified DNAs in laboratory stocks of Leishmania tarentolae: extrachromosomal circles structurally and functionally similar to the inverted-H-region amplification of methotrexate-resistant Leishmania major.
We describe the structure of amplified DNA that was discovered in two laboratory stocks of the protozoan parasite Leishmania tarentolae. Restriction mapping and molecular cloning revealed that a region of 42 kilobases was amplified 8- to 30-fold in these lines. Southern blot analyses of digested DNA...
Zapisane w:
| Wydane w: | Mol Cell Biol |
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| Główni autorzy: | , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis
1988
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3244352/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.12.5188-5199.1988 |
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