The secreted lymphangiogenic factor CCBE1 is essential for fetal liver erythropoiesis

The secreted protein CCBE1 is required for lymphatic vessel growth in fish and mice, and mutations in the CCBE1 gene cause Hennekam syndrome, a primary human lymphedema. Here we show that loss of CCBE1 also confers severe anemia in midgestation mouse embryos due to defective definitive erythropoiesi...

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Detalhes bibliográficos
Main Authors: Zou, Zhiying, Enis, David R., Bui, Hung, Khandros, Eugene, Kumar, Vinayak, Jakus, Zoltan, Thom, Christopher, Yang, Yiqing, Dhillon, Veerpal, Chen, Mei, Lu, MinMin, Weiss, Mitchell J., Kahn, Mark L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655737/
https://ncbi.nlm.nih.gov/pubmed/23426945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-462689
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