Corepressor Rcor1 is essential for murine erythropoiesis

The corepressor Rcor1 has been linked biochemically to hematopoiesis, but its function in vivo remains unknown. We show that mice deleted for Rcor1 are profoundly anemic and die in late gestation. Definitive erythroid cells from mutant mice arrest at the transition from proerythroblast to basophilic...

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Hauptverfasser: Yao, Huilan, Goldman, Devorah C., Nechiporuk, Tamilla, Kawane, Sunita, McWeeney, Shannon K., Tyner, Jeffrey W., Fan, Guang, Kerenyi, Marc A., Orkin, Stuart H., Fleming, William H., Mandel, Gail
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2014
Schlagworte:
Red Cells, Iron, and Erythropoiesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023423/
https://ncbi.nlm.nih.gov/pubmed/24652990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-11-538678
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