Corepressor Rcor1 is essential for murine erythropoiesis

The corepressor Rcor1 has been linked biochemically to hematopoiesis, but its function in vivo remains unknown. We show that mice deleted for Rcor1 are profoundly anemic and die in late gestation. Definitive erythroid cells from mutant mice arrest at the transition from proerythroblast to basophilic...

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Detalhes bibliográficos
Main Authors: Yao, Huilan, Goldman, Devorah C., Nechiporuk, Tamilla, Kawane, Sunita, McWeeney, Shannon K., Tyner, Jeffrey W., Fan, Guang, Kerenyi, Marc A., Orkin, Stuart H., Fleming, William H., Mandel, Gail
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023423/
https://ncbi.nlm.nih.gov/pubmed/24652990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-11-538678
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