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Germline Epigenetic Regulation of KILLIN in Cowden and Cowden-Like Syndromes

CONTEXT: Germline loss-of-function PTEN mutations cause 80% of Cowden syndrome (CS), an autosomal dominant disorder characterized by high risks of breast, thyroid, and other cancers. A large heterogenous group of CS-like (CSL) individuals, who have various combinations of CS features but who do not...

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Hlavní autoři: Bennett, Kristi L., Mester, Jessica, Eng, Charis
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655326/
https://ncbi.nlm.nih.gov/pubmed/21177507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2010.1877
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