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Second Malignant Neoplasms in Patients With Cowden Syndrome With Underlying Germline PTEN Mutations

PURPOSE: Patients with Cowden syndrome (CS) with underlying germline PTEN mutations are at increased risk of breast, thyroid, endometrial, and renal cancers. To our knowledge, risk of subsequent cancers in these patients has not been previously explored or quantified. PATIENTS AND METHODS: We conduc...

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Detalhes bibliográficos
Main Authors: Ngeow, Joanne, Stanuch, Kim, Mester, Jessica L., Barnholtz-Sloan, Jill S., Eng, Charis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039869/
https://ncbi.nlm.nih.gov/pubmed/24778394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2013.53.6656
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