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Germline PTEN, SDHB-D and KLLN Alterations in Endometrial Cancer Patients with Cowden and Cowden-Like Syndrome: an International Multi-Center Prospective Study

BACKGROUND: Endometrial cancer (EC) has only been recently recognized as a major component in Cowden syndrome (CS). Germline PTEN (PTEN_mut+), SDHB-D (SDHx_var+) and KLLN (KLLN_Me+) alterations cause CS and CS-like (CSL) phenotypes. This study aims to identify prevalence and clinico-pathologic predi...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Mahdi, Haider, Mester, Jessica L., Nizialek, Emily A., Ngeow, Joanne, Michener, Chad, Eng, Charis
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339629/
https://ncbi.nlm.nih.gov/pubmed/25376524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.29106
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