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Germline PIK3CA and AKT1 Mutations in Cowden and Cowden-like Syndromes
Cowden syndrome (CS) is a difficult-to-recognize multiple hamartoma syndrome with high risks of breast, thyroid, and other cancers. Germline mutations in PTEN on 10q23 were found to cause 85% of CS when accrued from tertiary academic centers, but prospective accrual from the community over the last...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3542473/ https://ncbi.nlm.nih.gov/pubmed/23246288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.10.021 |
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