mTOR REGULATES TAU PHOSPHORYLATION AND DEGRADATION: IMPLICATIONS FOR ALZHEIMER’S DISEASE AND OTHER TAUOPATHIES

Accumulation of tau is a critical event in several neurodegenerative disorders, collectively known as tauopathies, which include Alzheimer’s disease and frontotemporal dementia. Pathological tau is hyperphosphorylated and aggregates to form neurofibrillary tangles. The molecular mechanisms leading t...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Caccamo, Antonella, Magrì, Andrea, Medina, David X., Wisely, Elena V., López-Aranda, Manuel F., Silva, Alcino J., Oddo, Salvatore
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655115/
https://ncbi.nlm.nih.gov/pubmed/23425014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12057
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky