Oncogenic activation of p185neu stimulates tyrosine phosphorylation in vivo.
p185, the product of the neu/erbB2 proto-oncogene, is oncogenically activated by a point mutation that substitutes glutamic acid for valine in the transmembrane domain of the protein. We have found that the transforming form of p185 differs from its normal counterpart in inducing increased tyrosine...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365461/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2464744/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.9.3969-3973.1988 |
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