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Increased tyrosine kinase activity associated with the protein encoded by the activated neu oncogene.

A single mutation altering the transmembrane domain of the receptor-like p185 protein encoded by the rat neu gene converts the normal neu gene into a potent oncogene. The biochemical consequences of this mutation were studied by examining phosphorylation of the normal and transforming p185 molecules...

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Bibliografske podrobnosti
Main Authors: Bargmann, C I, Weinberg, R A
Format: Artigo
Jezik:Inglês
Izdano: 1988
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC281763/
https://ncbi.nlm.nih.gov/pubmed/2899890
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