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Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity.

Amplification and overexpression of the neu (c-erbB2) proto-oncogene has been implicated in the pathogenesis of 20 to 30% of human breast cancers. Although the activation of Neu receptor tyrosine kinase appears to be a pivotal step during mammary tumorigenesis, the mechanism by which Neu signals cel...

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Bibliografiska uppgifter
Huvudupphovsmän: Muthuswamy, S K, Siegel, P M, Dankort, D L, Webster, M A, Muller, W J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1994
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC358422/
https://ncbi.nlm.nih.gov/pubmed/7903421
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