Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity.
Amplification and overexpression of the neu (c-erbB2) proto-oncogene has been implicated in the pathogenesis of 20 to 30% of human breast cancers. Although the activation of Neu receptor tyrosine kinase appears to be a pivotal step during mammary tumorigenesis, the mechanism by which Neu signals cel...
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| Опубликовано в:: | Mol Cell Biol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
1994
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358422/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7903421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.1.735-743.1994 |
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