Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity.

Amplification and overexpression of the neu (c-erbB2) proto-oncogene has been implicated in the pathogenesis of 20 to 30% of human breast cancers. Although the activation of Neu receptor tyrosine kinase appears to be a pivotal step during mammary tumorigenesis, the mechanism by which Neu signals cel...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Muthuswamy, S K, Siegel, P M, Dankort, D L, Webster, M A, Muller, W J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358422/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7903421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.1.735-743.1994
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