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A novel bispecific antibody recruits T cells to eradicate tumors in the “immunologically privileged” central nervous system
Bispecific T-cell engagers (BiTEs) may break multiple barriers that currently limit the use of immunotherapy in glioblastoma patients. We have recently described a novel BiTE specific for a mutated form of the epidermal growth factor receptor, EGFRvIII, that exerts potent antineoplastic effects agai...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3654588/ https://ncbi.nlm.nih.gov/pubmed/23734318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.23639 |
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