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Improving the Design of a MscL-Based Triggered Nanovalve

The mechanosensitive channel of large conductance, MscL, has been proposed as a triggered nanovalve to be used in drug release and other nanodevices. It is a small homopentameric bacterial protein that has the largest gated pore known: greater than 30 Å. Large molecules, even small proteins can be r...

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Autors principals: Iscla, Irene, Eaton, Christina, Parker, Juandell, Wray, Robin, Kovács, Zoltán, Blount, Paul
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652633/
https://ncbi.nlm.nih.gov/pubmed/23678232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bios3010171
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