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Harnessing synthetic lethal interactions in anticancer drug discovery
Unique features of tumours that can be exploited by targeted therapies are a key focus of current cancer research. One such approach is known as synthetic lethality screening, which involves searching for genetic interactions of two mutations whereby the presence of either mutation alone has no effe...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3652585/ https://ncbi.nlm.nih.gov/pubmed/21532565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3374 |
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