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SynLethDB: synthetic lethality database toward discovery of selective and sensitive anticancer drug targets

Synthetic lethality (SL) is a type of genetic interaction between two genes such that simultaneous perturbations of the two genes result in cell death or a dramatic decrease of cell viability, while a perturbation of either gene alone is not lethal. SL reflects the biologically endogenous difference...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Guo, Jing, Liu, Hui, Zheng, Jie
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702809/
https://ncbi.nlm.nih.gov/pubmed/26516187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1108
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