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SynLethDB: synthetic lethality database toward discovery of selective and sensitive anticancer drug targets
Synthetic lethality (SL) is a type of genetic interaction between two genes such that simultaneous perturbations of the two genes result in cell death or a dramatic decrease of cell viability, while a perturbation of either gene alone is not lethal. SL reflects the biologically endogenous difference...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4702809/ https://ncbi.nlm.nih.gov/pubmed/26516187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1108 |
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