Tolerance to MHC class II disparate allografts through genetic modification of bone marrow

Induction of molecular chimerism through genetic modification of bone marrow is a powerful tool for the induction of tolerance. Here we demonstrate for the first time that expression of an allogeneic MHC class II gene in autologous bone marrow cells, resulting in a state of molecular chimerism, indu...

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Bibliographic Details
Main Authors: Jindra, Peter T., Tripathi, Sudipta, Tian, Chaorui, Iacomini, John, Bagley, Jessamyn
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651743/
https://ncbi.nlm.nih.gov/pubmed/22833118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2012.57
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