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Induction of transplantation tolerance to fully mismatched cardiac allografts by T cell mediated delivery of alloantigen

Induction of transplantation tolerance has the potential to allow for allograft acceptance without the need for life-long immunosuppression. Here we describe a novel approach that uses delivery of alloantigen by mature T cells to induce tolerance to fully allogeneic cardiac grafts. Adoptive transfer...

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Main Authors: Tian, Chaorui, Yuan, Xueli, Jindra, Peter T., Bagley, Jessamyn, Sayegh, Mohamed H., Iacomini, John
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991109/
https://ncbi.nlm.nih.gov/pubmed/20452826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.04.012
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