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The Indirect Alloresponse Impairs the Induction but not Maintenance of Tolerance to MHC Class I-Disparate Allografts

We studied the effects of indirect allorecognition on the induction and maintenance phases of tolerance in miniature swine cotransplanted with heart and kidney allografts. MHC class I-mismatched heart and kidney grafts were cotransplanted in recipients receiving CyA for 12 days. Recipients were unim...

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Detalhes bibliográficos
Main Authors: Weiss, Matthew J., Guenther, Dax A., Mezrich, Joshua D., Sahara, Hisashi, Ng, Choo Y., Meltzer, Andrew J., Sayre, Jessica K., Cochrane, Meghan E., Pujara, Akshat C., Houser, Stuart L., Sachs, David H., Rosengard, Bruce R., Allan, James S., Benichou, Gilles, Madsen, Joren C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252388/
https://ncbi.nlm.nih.gov/pubmed/19145702
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