Regulated expression of a complete human beta-globin gene encoded by a transmissible retrovirus vector.
We introduced a human beta-globin gene into murine erythroleukemia (MEL) cells by infection with recombinant retroviruses containing the complete genomic globin sequence. The beta-globin gene was correctly regulated during differentiation, steady-state mRNA levels being induced 5- to 30-fold after t...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1987
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365147/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3029570/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.2.887-897.1987 |
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