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Regulated expression of a complete human beta-globin gene encoded by a transmissible retrovirus vector.

We introduced a human beta-globin gene into murine erythroleukemia (MEL) cells by infection with recombinant retroviruses containing the complete genomic globin sequence. The beta-globin gene was correctly regulated during differentiation, steady-state mRNA levels being induced 5- to 30-fold after t...

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Bibliografische gegevens
Hoofdauteurs: Cone, R D, Weber-Benarous, A, Baorto, D, Mulligan, R C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1987
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC365147/
https://ncbi.nlm.nih.gov/pubmed/3029570
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