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Biglycan fragmentation in pathologies associated with extracellular matrix remodeling by matrix metalloproteinases

BACKGROUND: The proteoglycan biglycan (BGN) is involved in collagen fibril assembly and its fragmentation is likely to be associated with collagen turnover during the pathogenesis of diseases which involve dysregulated extracellular matrix remodeling (ECMR), such as rheumatoid arthritis (RA) and liv...

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Détails bibliographiques
Auteurs principaux: Genovese, Federica, Barascuk, Natasha, Larsen, Lise, Larsen, Martin Røssel, Nawrocki, Arkadiusz, Li, Yili, Zheng, Qinlong, Wang, Jianxia, Veidal, Sanne Skovgård, Leeming, Diana Julie, Karsdal, Morten Asser
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651402/
https://ncbi.nlm.nih.gov/pubmed/23635022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-6-9
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