Measurement of CO3-610, a Potential Liver Biomarker Derived from Matrix Metalloproteinase-9 Degradation of Collagen Type III, in a Rat Model of Reversible Carbon-Tetrachloride-Induced Fibrosis

BACKGROUND AND AIM: The current study utilized a carbon tetrachloride (CCl(4))-induced liver fibrosis model to measure levels of the MMP9-mediated collagen type III degradation fragment CO3-610 (site of cleavage: KNGETGPQGP), during disease progression and regression, and to investigate a potential...

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Detalhes bibliográficos
Principais autores: Vassiliadis, Efstathios, Larsen, Dorthe Vang, Clausen, Rikke Elgaard, Veidal, Sanne Skovgård, Barascuk, Natasha, Larsen, Lise, Simonsen, Henrik, Segovia-Silvestre, Toni, Hansen, Christina, Overgaard, Trine, Leeming, Diana Julie, Karsdal, Morten A
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076019/
https://ncbi.nlm.nih.gov/pubmed/21499440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BMI.S6347
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