Circulating CO3-610, a degradation product of collagen III, closely reflects liver collagen and portal pressure in rats with fibrosis

BACKGROUND: Hepatic fibrosis is characterized by intense tissue remodeling, mainly driven by matrix metalloproteinases. We previously identified CO3-610, a type III collagen neoepitope generated by matrix metalloproteinase (MMP)-9, and tested its performance as a fibrosis marker in rats with bile-du...

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Main Authors: Segovia-Silvestre, Toni, Reichenbach, Vedrana, Fernández-Varo, Guillermo, Vassiliadis, Efstathios, Barascuk, Natasha, Morales-Ruiz, Manuel, Karsdal, Morten A, Jiménez, Wladimiro
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170588/
https://ncbi.nlm.nih.gov/pubmed/21813019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-4-19
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