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Biglycan fragmentation in pathologies associated with extracellular matrix remodeling by matrix metalloproteinases

BACKGROUND: The proteoglycan biglycan (BGN) is involved in collagen fibril assembly and its fragmentation is likely to be associated with collagen turnover during the pathogenesis of diseases which involve dysregulated extracellular matrix remodeling (ECMR), such as rheumatoid arthritis (RA) and liv...

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Dettagli Bibliografici
Autori principali: Genovese, Federica, Barascuk, Natasha, Larsen, Lise, Larsen, Martin Røssel, Nawrocki, Arkadiusz, Li, Yili, Zheng, Qinlong, Wang, Jianxia, Veidal, Sanne Skovgård, Leeming, Diana Julie, Karsdal, Morten Asser
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651402/
https://ncbi.nlm.nih.gov/pubmed/23635022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-6-9
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