Biglycan fragmentation in pathologies associated with extracellular matrix remodeling by matrix metalloproteinases

BACKGROUND: The proteoglycan biglycan (BGN) is involved in collagen fibril assembly and its fragmentation is likely to be associated with collagen turnover during the pathogenesis of diseases which involve dysregulated extracellular matrix remodeling (ECMR), such as rheumatoid arthritis (RA) and liv...

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Detalhes bibliográficos
Main Authors: Genovese, Federica, Barascuk, Natasha, Larsen, Lise, Larsen, Martin Røssel, Nawrocki, Arkadiusz, Li, Yili, Zheng, Qinlong, Wang, Jianxia, Veidal, Sanne Skovgård, Leeming, Diana Julie, Karsdal, Morten Asser
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651402/
https://ncbi.nlm.nih.gov/pubmed/23635022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-6-9
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