Biglycan fragmentation in pathologies associated with extracellular matrix remodeling by matrix metalloproteinases

BACKGROUND: The proteoglycan biglycan (BGN) is involved in collagen fibril assembly and its fragmentation is likely to be associated with collagen turnover during the pathogenesis of diseases which involve dysregulated extracellular matrix remodeling (ECMR), such as rheumatoid arthritis (RA) and liv...

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Bibliografische gegevens
Hoofdauteurs: Genovese, Federica, Barascuk, Natasha, Larsen, Lise, Larsen, Martin Røssel, Nawrocki, Arkadiusz, Li, Yili, Zheng, Qinlong, Wang, Jianxia, Veidal, Sanne Skovgård, Leeming, Diana Julie, Karsdal, Morten Asser
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2013
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651402/
https://ncbi.nlm.nih.gov/pubmed/23635022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-6-9
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