Lrp5 and Lrp6 Exert Overlapping Functions in Osteoblasts during Postnatal Bone Acquisition

The canonical Wnt signaling pathway is critical for skeletal development and maintenance, but the precise roles of the individual Wnt co-receptors, Lrp5 and Lrp6, that enable Wnt signals to be transmitted in osteoblasts remain controversial. In these studies, we used Cre-loxP recombination, in which...

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Autors principals: Riddle, Ryan C., Diegel, Cassandra R., Leslie, Julie M., Van Koevering, Kyle K., Faugere, Marie-Claude, Clemens, Thomas L., Williams, Bart O.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651091/
https://ncbi.nlm.nih.gov/pubmed/23675479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063323
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