Lrp5 and Lrp6 Exert Overlapping Functions in Osteoblasts during Postnatal Bone Acquisition

The canonical Wnt signaling pathway is critical for skeletal development and maintenance, but the precise roles of the individual Wnt co-receptors, Lrp5 and Lrp6, that enable Wnt signals to be transmitted in osteoblasts remain controversial. In these studies, we used Cre-loxP recombination, in which...

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Autori principali: Riddle, Ryan C., Diegel, Cassandra R., Leslie, Julie M., Van Koevering, Kyle K., Faugere, Marie-Claude, Clemens, Thomas L., Williams, Bart O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651091/
https://ncbi.nlm.nih.gov/pubmed/23675479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063323
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