Wnt-Lrp5 Signaling Regulates Fatty Acid Metabolism in the Osteoblast

The Wnt coreceptors Lrp5 and Lrp6 are essential for normal postnatal bone accrual and osteoblast function. In this study, we identify a previously unrecognized skeletal function unique to Lrp5 that enables osteoblasts to oxidize fatty acids. Mice lacking the Lrp5 coreceptor specifically in osteoblas...

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Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Frey, Julie L., Li, Zhu, Ellis, Jessica M., Zhang, Qian, Farber, Charles R., Aja, Susan, Wolfgang, Michael J., Clemens, Thomas L., Riddle, Ryan C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2015
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420919/
https://ncbi.nlm.nih.gov/pubmed/25802278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01343-14
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