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Wnt-Lrp5 Signaling Regulates Fatty Acid Metabolism in the Osteoblast
The Wnt coreceptors Lrp5 and Lrp6 are essential for normal postnatal bone accrual and osteoblast function. In this study, we identify a previously unrecognized skeletal function unique to Lrp5 that enables osteoblasts to oxidize fatty acids. Mice lacking the Lrp5 coreceptor specifically in osteoblas...
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| Publicado no: | Mol Cell Biol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4420919/ https://ncbi.nlm.nih.gov/pubmed/25802278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01343-14 |
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