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Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition

Global energy balance in mammals is controlled by the actions of circulating hormones that coordinate fuel production and utilization in metabolically active tissues. Bone-derived osteocalcin, in its undercarboxylated, hormonal form, regulates fat deposition and is a potent insulin secretagogue. Her...

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Huvudupphovsmän: Fulzele, Keertik, Riddle, Ryan C., Cao, Xuemei, Wan, Chao, Chen, Dongquan, Faugere, Marie-Claude, Aja, Susan, Hussain, Mehboob A., Brüning, Jens C., Clemens, Thomas L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925155/
https://ncbi.nlm.nih.gov/pubmed/20655471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.06.002
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