Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition

Global energy balance in mammals is controlled by the actions of circulating hormones that coordinate fuel production and utilization in metabolically active tissues. Bone-derived osteocalcin, in its undercarboxylated, hormonal form, regulates fat deposition and is a potent insulin secretagogue. Her...

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Main Authors: Fulzele, Keertik, Riddle, Ryan C., Cao, Xuemei, Wan, Chao, Chen, Dongquan, Faugere, Marie-Claude, Aja, Susan, Hussain, Mehboob A., Brüning, Jens C., Clemens, Thomas L.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925155/
https://ncbi.nlm.nih.gov/pubmed/20655471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.06.002
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