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Lrp5 and Lrp6 play compensatory roles in mouse intestinal development
Low-density lipoprotein receptor–related proteins 5 and 6 (Lrp5 and Lrp6) are co-receptors of Wnt ligands and play important roles in Wnt/β-catenin signal transduction. Mice homozygous for a germline deletion of Lrp6 die at birth with several associated defects, while Lrp5-deficient mice are viable....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3245350/ https://ncbi.nlm.nih.gov/pubmed/21866564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23324 |
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