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Lrp5 and Lrp6 play compensatory roles in mouse intestinal development

Low-density lipoprotein receptor–related proteins 5 and 6 (Lrp5 and Lrp6) are co-receptors of Wnt ligands and play important roles in Wnt/β-catenin signal transduction. Mice homozygous for a germline deletion of Lrp6 die at birth with several associated defects, while Lrp5-deficient mice are viable....

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Zhong, Zhendong, Baker, Jacob J., Zylstra-Diegel, Cassandra R., Williams, Bart O.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245350/
https://ncbi.nlm.nih.gov/pubmed/21866564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23324
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