Chargement en cours...

A Novel Mechanism for Adenylyl Cyclase Inhibition from the Crystal Structure of Its Complex with Catechol Estrogen()

Catechol estrogens are steroid metabolites that elicit physiological responses through binding to a variety of cellular targets. We show here that catechol estrogens directly inhibit soluble adenylyl cyclases and the abundant trans-membrane adenylyl cyclases. Catechol estrogen inhibition is non-comp...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Steegborn, Clemens, Litvin, Tatiana N., Hess, Kenneth C., CapperM, Austin B., Taussig, Ronald, Buck, Jochen, Levin, Lonny R., Wu, Hao
Format: Artigo
Langue:Inglês
Publié: 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650720/
https://ncbi.nlm.nih.gov/pubmed/16002394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M507144200
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!