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Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons

BACKGROUND: Activation of proto-oncogenes by DNA amplification is an important mechanism in the development and maintenance of cancer cells. Until recently, identification of the targeted genes relied on labour intensive and time consuming positional cloning methods. In this study, we outline a stra...

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Publicat a:BMC Genomics
Autors principals: De Preter, Katleen, Pattyn, Filip, Berx, Geert, Strumane, Kristin, Menten, Björn, Van Roy, Frans, De Paepe, Anne, Speleman, Frank, Vandesompele, Jo
Format: Artigo
Idioma:Inglês
Publicat: BMC 2004
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365025/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15018647/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2164-5-11
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