Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons

BACKGROUND: Activation of proto-oncogenes by DNA amplification is an important mechanism in the development and maintenance of cancer cells. Until recently, identification of the targeted genes relied on labour intensive and time consuming positional cloning methods. In this study, we outline a stra...

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I whakaputaina i:	BMC Genomics
Ngā kaituhi matua:	De Preter, Katleen, Pattyn, Filip, Berx, Geert, Strumane, Kristin, Menten, Björn, Van Roy, Frans, De Paepe, Anne, Speleman, Frank, Vandesompele, Jo
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2004
Ngā marau:	Research Article
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365025/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15018647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2164-5-11
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