Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons

BACKGROUND: Activation of proto-oncogenes by DNA amplification is an important mechanism in the development and maintenance of cancer cells. Until recently, identification of the targeted genes relied on labour intensive and time consuming positional cloning methods. In this study, we outline a stra...

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Publié dans:	BMC Genomics
Auteurs principaux:	De Preter, Katleen, Pattyn, Filip, Berx, Geert, Strumane, Kristin, Menten, Björn, Van Roy, Frans, De Paepe, Anne, Speleman, Frank, Vandesompele, Jo
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2004
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365025/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15018647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2164-5-11
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