Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons

BACKGROUND: Activation of proto-oncogenes by DNA amplification is an important mechanism in the development and maintenance of cancer cells. Until recently, identification of the targeted genes relied on labour intensive and time consuming positional cloning methods. In this study, we outline a stra...

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Pubblicato in:	BMC Genomics
Autori principali:	De Preter, Katleen, Pattyn, Filip, Berx, Geert, Strumane, Kristin, Menten, Björn, Van Roy, Frans, De Paepe, Anne, Speleman, Frank, Vandesompele, Jo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2004
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365025/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15018647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2164-5-11
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