The Lipid Kinase Phosphatidylinositol-4 Kinase III Alpha Regulates the Phosphorylation Status of Hepatitis C Virus NS5A

The lipid kinase phosphatidylinositol 4-kinase III alpha (PI4KIIIα) is an essential host factor of hepatitis C virus (HCV) replication. PI4KIIIα catalyzes the synthesis of phosphatidylinositol 4-phosphate (PI4P) accumulating in HCV replicating cells due to enzyme activation resulting from its intera...

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Detalhes bibliográficos
Main Authors: Reiss, Simon, Harak, Christian, Romero-Brey, Inés, Radujkovic, Danijela, Klein, Rahel, Ruggieri, Alessia, Rebhan, Ilka, Bartenschlager, Ralf, Lohmann, Volker
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3649985/
https://ncbi.nlm.nih.gov/pubmed/23675303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003359
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