Mapping of Functional Domains of the Lipid Kinase Phosphatidylinositol 4-Kinase Type III Alpha Involved in Enzymatic Activity and Hepatitis C Virus Replication

The lipid kinase phosphatidylinositol 4-kinase III alpha (PI4KIIIα) is an endoplasmic reticulum (ER)-resident enzyme that synthesizes phosphatidylinositol 4-phosphate (PI4P). PI4KIIIα is an essential host factor for hepatitis C virus (HCV) replication. Interaction with HCV nonstructural protein 5A (...

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Detalhes bibliográficos
Main Authors: Harak, Christian, Radujkovic, Danijela, Taveneau, Cyntia, Reiss, Simon, Klein, Rahel, Bressanelli, Stéphane, Lohmann, Volker
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136347/
https://ncbi.nlm.nih.gov/pubmed/24920820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01063-14
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