LAB/NTAL Facilitates Fungal/PAMP-induced IL-12 and IFN-γ Production by Repressing β-Catenin Activation in Dendritic Cells

Fungal pathogens elicit cytokine responses downstream of immunoreceptor tyrosine-based activation motif (ITAM)-coupled or hemiITAM-containing receptors and TLRs. The Linker for Activation of B cells/Non-T cell Activating Linker (LAB/NTAL) encoded by Lat2, is a known regulator of ITAM-coupled recepto...

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Αποθηκεύτηκε σε:
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Κύριοι συγγραφείς: Orr, Selinda J., Burg, Ashley R., Chan, Tim, Quigley, Laura, Jones, Gareth W., Ford, Jill W., Hodge, Deborah, Razzook, Catherine, Sarhan, Joseph, Jones, Yava L., Whittaker, Gillian C., Boelte, Kimberly C., Lyakh, Lyudmila, Cardone, Marco, O'Connor, Geraldine M., Tan, Cuiyan, Li, Hongchuan, Anderson, Stephen K., Jones, Simon A., Zhang, Weiguo, Taylor, Philip R., Trinchieri, Giorgio, McVicar, Daniel W.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2013
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3649983/
https://ncbi.nlm.nih.gov/pubmed/23675302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003357
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