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The clathrin adaptor complexes as a paradigm for membrane-associated allostery

The clathrin-associated adaptor protein (AP) complexes AP-1 and AP-2 are two members of a family of heterotetrameric assemblies that connect transmembrane protein cargo to vesicular coats. Cargo binding by AP-1 is activated by the small GTPase Arf1, while AP-2 is activated by the phosphoinositide PI...

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Detalhes bibliográficos
Main Authors: Canagarajah, Bertram J, Ren, Xuefeng, Bonifacino, Juan S, Hurley, James H
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3649254/
https://ncbi.nlm.nih.gov/pubmed/23424177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2235
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