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Physiology of the intrathecal bolus: the leptomeningeal route for macromolecule and particle delivery to CNS

Presently, there are no effective treatments for several diseases involving the CNS, which is protected by the blood-brain, blood-CSF and blood-arachnoid barriers. Traversing any of these barriers is difficult, especially for macromolecular drugs and particulates. However, there is significant exper...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Papisov, Mikhail I., Belov, Vasily V., Gannon, Kimberley S.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646927/
https://ncbi.nlm.nih.gov/pubmed/23316936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300474m
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