A prognostic signature of G₂ checkpoint function in melanoma cell lines

As DNA damage checkpoints are barriers to carcinogenesis, G(2) checkpoint function was quantified to test for override of this checkpoint during melanomagenesis. Primary melanocytes displayed an effective G(2) checkpoint response to ionizing radiation (IR)-induced DNA damage. Thirty-seven percent of...

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Main Authors: Omolo, Bernard, Carson, Craig, Chu, Haitao, Zhou, Yingchun, Simpson, Dennis A., Hesse, Jill E., Paules, Richard S., Nyhan, Kristine C., Ibrahim, Joseph G., Kaufmann, William K.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646863/
https://ncbi.nlm.nih.gov/pubmed/23454897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24067
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