Gene expression signatures but not cell cycle checkpoint functions distinguish AT carriers from normal individuals

Ataxia telangiectasia (AT) is a rare autosomal recessive disease caused by mutations in the ataxia telangiectasia-mutated gene (ATM). AT carriers with one mutant ATM allele are usually not severely affected although they carry an increased risk of developing cancer. There has not been an easy and re...

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Main Authors: Zhang, Liwen, Simpson, Dennis A., Innes, Cynthia L., Chou, Jeff, Bushel, Pierre R., Paules, Richard S., Kaufmann, William K., Zhou, Tong
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2013
Assuntos:
Biomarkers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798780/
https://ncbi.nlm.nih.gov/pubmed/23943852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00064.2013
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