Gene expression signatures but not cell cycle checkpoint functions distinguish AT carriers from normal individuals

Ataxia telangiectasia (AT) is a rare autosomal recessive disease caused by mutations in the ataxia telangiectasia-mutated gene (ATM). AT carriers with one mutant ATM allele are usually not severely affected although they carry an increased risk of developing cancer. There has not been an easy and re...

詳細記述

保存先:
書誌詳細
主要な著者: Zhang, Liwen, Simpson, Dennis A., Innes, Cynthia L., Chou, Jeff, Bushel, Pierre R., Paules, Richard S., Kaufmann, William K., Zhou, Tong
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2013
主題:
Biomarkers
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798780/
https://ncbi.nlm.nih.gov/pubmed/23943852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00064.2013
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